Tissue-engineered valved conduits in the pulmonary circulation

Percutaneous pulmonary valve replacement: autologous tissue-engineered valved stents.

AIMS Percutaneous implantation has already been used clinically and is a great option for treating young patients. The use of autologous tissue-engineered valved stents might solve the problem of degeneration and limited durability of biological heart valves. METHODS AND RESULTS Porcine pulmonary heart valves and small intestinal submucosa were obtained from a slaughterhouse. The intestinal s...

Doppler evaluation of homograft valved conduits in children.

To assess the flow characteristics of homograft valved conduits in the immediate postoperative period, 69 children with 71 homograft conduits underwent 2-dimensional and Doppler echocardiographic examination at 1 to 40 days (mean 8) after surgery. Of the 71 conduits studied, 19 were aortic and 52 were pulmonary homograft valved conduits. Two aortic homograft valved conduits were inserted in the...

Valved Conduits Right Ventricle to Pulmonary Artery for Complex Congenital Heart Defects

Decellularization of human donor aortic and pulmonary valved conduits using low concentration sodium dodecyl sulfate

The clinical use of decellularized cardiac valve allografts is increasing. Long-term data will be required to determine whether they outperform conventional cryopreserved allografts. Valves decellularized using different processes may show varied long-term outcomes. It is therefore important to understand the effects of specific decellularization technologies on the characteristics of donor hea...

Composite valved apico-aortic conduits for left ventricular outflow obstruction.

Problems related to the left ventricular outflow tract are not always amenable to conven— tional surgical metiuxis. and in some cases may be solved with the creation of a double ouclet left ventricle, using a composite rigid pyrolitc lcÍt ventricular apex outlet prosthcsis and a fabric valve-containing conduit. The prilnary indicacion for apico—aortic conduirs is severe left ventricular outlet ...